Griffonia simplicifolia is a woody climbing shrub native to West Africa and Central Africa. It grows to about 3 m, and bears greenish flowers followed by black pods.The seeds of the plant are used as an herbal supplement for their 5-hydroxytryptophan (5-HTP ) content. 5-Hydroxytryptophan is an important building block for the human body to form serotonin, a neurotransmitter. In one "randomized, double-blind, placebo-controlled trial" in 2010 Griffonia simplicifolia extract, administered via oral spray to twenty overweight females resulting in increased satiety.
5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), its molecular formula：C11H12N2O3
is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitters serotonin and melatonin from tryptophan.5-HTP is sold over the counter in the United States, Canada, and the United Kingdom as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid. It is also marketed in many European countries for the indication of major depression under the trade names Cincofarm, Levothym, Levotonine, Oxyfan, Telesol, Tript-OH, and Triptum.
Griffonia Seed Extract 5-htp/5 htp has a wide range of applications.for example,as the raw materials of drug anti-bacterial, anti-depressants, antitumor and sedation, used in fields of pharmaceutical and health products,and as dietary supplements increased therapeutic function,used in fields of dietary supplement products.