Rosemary Extract Carnosic acid
● Name : Rosemary Extract Carnosic acid
● Source: Rosemary
● Botanical Name : Rosmarinus officinalis
● Extract part: Leaf
● Composition : Carnosic acid
● Appearance: Fine Brownish Yellow powder
● Country of origin:P.R. China
Rosmarinus officinalis L. from Lamiaceae family, is commonly known as rosemary. Rosemary is a widely cultivated herbal plant that is originated in the Mediterranean area. Rosemary is an aromatic evergreen shrub with leaves similar to hemlock needles .The leaves are used as a flavoring in foods and a prescription for treating minor ailments including :gout, cough, headache, high blood pressure, and reducing age-related memory loss.
Rosemary is used topically for preventing and treating baldness by applying to the skin ; and treating circulation problems, toothache, a skin condition called eczema, and joint or muscle pain such as myalgia, sciatica, and intercostal neuralgia. It is also used for wound healing, in bath therapy (balneotherapy), and as an insect repellent.
Rosemary contains a number of phytochemicals, including rosmarinic acid, camphor, caffeic acid, ursolic acid, betulinic acid, rosmanol and the antioxidants carnosic acid and carnosol.
Rosmarinic acid is a chemical compound firstly found in Rosmarinus officinalis which has antioxidant properties.
Another main antioxidant in rosemary is the phenolic diterpene carnosic acid ,appears to be the main substance for general oxidation leading to artifacts withγ-or δ-lactone structure in extracts of Rosmarinus officinalis .
Rosmarinic acid is a caffeic acid ester of salvianic acid A that acts as a GABA transaminase inhibitor, more specifically on 4-aminobutyrate transaminase.Rosmarinic acid also inhibits the expression of indoleamine 2,3-dioxygenase via its cyclooxygenase-inhibiting properties.
Constituents in Rosemary extracts from Rosmarinus officinalis L contains several compounds proven to have antioxidative function
Carnosic acid, a phenolic diterpene, exhibited potent antioxidant and anticancer properties in both in vivo and in vitro conditions .
Study on Human respiratory syncytial virus (hRSV) revealed the bioactive constituent of an extract of Rosmarinus officinalis,carnosic acid , exerted a strong inhibitory effect against hRSV infection.
The importance of free radical-induced oxidative damage after traumatic brain injury (TBI) has been well documented.
Carnosic acid is known to has multiple potent biochemical activities including antioxidant,antiviral ,anticancer and anti-inflammatory.Researches suggested that Carnosic acid has potential application in medical treatment .