High Quality 50% Chlorogenic Acid Honey Suckle Flower Extract

High Quality 50% Chlorogenic Acid Honey Suckle Flower Extract

● Name:Honeysuckle extract
● SN(Serial No.):R052.
● Specifications:5:1TLC.
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● Name:Honeysuckle extract 

● SN(Serial No.):R052. 

● Specifications:5:1TLC. 


● EINECS/ELINCS No.:283-263-6 

● CAS:84603-62-3,223749-79-9 

● Chem/IUPAC Name:Lonicera Caprifolium Extract is an extract of the flowers of the honeysuckle, Lonicera caprifolium,Caprifoliaceae,Lonicera Japonica Extract is an extract of the flowers of Lonicera japonica, Caprifoliaceae 


● Basic Botanical Data of Honeysuckle flower. 

● Constituents and Phytochemicals:Honeysuckle flower. 

● Effects and History of Honeysuckle flower. 

● Honeysuckle flower:Indications,Combinations and Pharmacology. 

● More Applications and function of Honeysuckle flower. 

● Honeysuckle flower:Suggestions and Administration. 

● Research Update:Honeysuckle flower. 

Constituents and Phytochemicals:Honeysuckle flower.: 


Honeysuckle's constituents include a volatile oil, tannins, and salicylic acid.Honeysuckle contains a volatile oil (which includes linalool and jasmone) , tannins, luteolin, and inositol.This herb contains cyclohexanhexol, flavonoids, inositol, saponin, tannin, etc.


Its leaves contain flavolin, tannin and saponin and its stems saponin.Chlorogenic acid; Isochlorogenic acid; Ginnol; (-sitosterol; Stigmasterol; Linalool; Ethyl palmitate; Methylinoleate; Ethyl linolenate; (-cubebene; Cis-3-hexen-1-ol; (-terppineol; Geraniol; Benzylbenzoate; 2-methyl-1-butanol; Benzyl alcohol; Phenethyl alcohol; Cis-linalool oxide; Eugenol; Carvacrol; (-hederin; Sapindoside B; Caffeic acid; Luteolin; Trans-linalool oxide; Fulyotomentoside A; 1,1'-bicyclohexyl; Trans-trans-farnesol; Stimasteryl-D-glucoside; (-sitosteryl-D-glucoside; (3-methyl-2(2-pentenyl)-2-cyclopenten-1-one; (Cis-2,6,6-trimethyl-2-vinyl-5-hydroxy-tetrahydropyran. 

Effects and History of Honeysuckle flower.:

For centuries Honeysuckle has been used in Chinese medicine for treating inflammation, fever and infection. The herb has also shown promise in combating certain malignant diseases, and is already highly regarded as an antibiotic that combats infection both internally and externally. Honeysuckle has also been used as a laxative, diuretic and blood purifier. 

Detoxicate; Clears away toxic substances.Clearing heat and detoxicating, removing heat from the blood and arresting dysentery. 

Kills or inhibits the action of germs. 

Cools and reduces fever and heat. 

Reduces ulcers, swell, sore throat, skin infection. 

Clears the lungs and strengthens general health. 

Honeysuckle is a familiar climbing, flowering plant whose many varieties grow worldwide. The flower's name is derived from the fact that children enjoy sucking the nectar from its blossoms.Honeysuckle has been used medicinally in China for generations, where it is employed in Traditional Chinese Medicine to clear heat and toxins from the body, but it has only recently been adopted by Western herbalists. 


Current studies in China have found Honeysuckle to be effective in reducing inflammation, fever and infection, and these studies have also indicated that Honeysuckle may have some promise in treating malignant breast disease. Chinese researchers think that Honeysuckle may help regulate blood sugar levels, thus theoretically helping to stave off adult onset diabetes. It has also been shown to inhibit tuberculosis. 

Honeysuckle also combines well with other herbs. It has been used in conjunction with Chrysanthemum to lower blood pressure, with Skullcap to reduce fever and with Cowslip or Elecampane as an expectorant. Honeysuckle is a natural source of salicylic acid, the compound from which aspirin is made, and can thus be used in cases of headache, joint pain and fevers. Honeysuckle has been used as a gargle for sore throats and mouth ulcers, and it may also be used as a mild laxative, diuretic and diaphoretic. Topically, Honeysuckle has been used to ease the pain of sunburn and reduce the itching of poison ivy and other rashes

Honeysuckle flower:Indications,Combinations and Pharmacology.:

Indications,Combinations:Honeysuckle flower 

1.Febrile diseases:


A) Exogenous pathogenic heat at the defensive and qi levels manifested as fever, thirst, slight aversion to wind and cold and sore throatHoneysuckle flower (Jinyinhua) is used with Forsythia fruit (Lianqiao) and Arctium fruit (Niubangzi); 

B) Exogenous pathogenic heat at the qi level manifested as high fever, extreme thirst and surging, big pulseHoneysuckle flower (Jinyinhua) is used with Gypsum (Shigao) and Anemarrhena rhizome (Zhimu); 


C) Exogenous pathogenic heat at the nutritive and blood levels manifested as maculopapule that appears as a dull, deep red and dry tongue, irritability and insomnia. Honeysuckle flower (Jinyinhua) is used with Moutan bark (Mudanpi) and Fresh rehmannia root (Shengdihuang). 

2.Boils, carbuncles and furuncles:Honeysuckle flower (Jinyinhua) is used alone or is combined with Dandelion herb (Pugongying), Chrysanthemum flower (Juhua) and Forsythia fruit (Lianqiao). 

3.Toxic heat diarrhea:Honeysuckle flower (Jinyinhua) is used with Coptis root (Huanglian) and Pulsatilla root (Baitouweng). 

4.For treating Carbuncle and Furuncles: 

(A) Initial attacks of carbuncles and furuncles with redness, heat sensation and pains: This herb can be decocted alone for drinking or its decoction residue can be used for application onto the affected part or it can also be used in combination with Chinese honeylocust spine (Spina Gleditsiae), pangolin scale and dahurian angelica root (Radix Angelicae Dahuricae), e.g., Xianfang Huoming Yin. 

(B) Furuncles with redness, heat sensation and pains, which are hard and deep-rooted: Use it with Chinese violet (Herba Violae), dandelion (Herba Taraxini) and mother chrysanthemum (Flos Chrysanthemi indici), e.g., Wuwei Xiaodu Yin. 


(C) Abdominal pain: Use it with Chinese angelica, garden burnet root (Radix Sanguisorbae) and skullcap root (Radix Scutellariae), e.g., Qing Yi Yin. 

(D) Pulmonary abscess with hemoptysis (expectoration of blood from some part of the respiratory tract) and hematemesis (vomiting of blood) with pus: Use it with houttuynia, common reed rhizome (Rhizoma Phragmitis), peach kernels, etc., in order to remove heat from the lungs to promote the discharge of pus. 

5.For treating initial attacks of febrile diseases due to affection by exopathogenic wind-heat: 

(A) Initial attacks of febrile diseases: Use it with weeping forsythia fruit (Fructus Forsythiae), peppermint, great burdock achene (Fructus Arctii), etc., e.g., Yin Qiao San. 

(B) Coma with deep-red tongue and little sleep due to vexation as a result of heat entering the blood: Use it with raw rehmannia, Chinese goldthread rhizome (Rhizoma Coptidis), etc., e.g., Qing Ying Tang, because this herb can eliminate the heat of the ying system through the qi system. 

6.For treating dysentery with bloody stools due to toxic heat: 

It can produce effects when it is decocted alone until thick and it can also be used with such herbs as skullcap root (Radix Scutellariae), Chinese goldthread rhizome (Rhizoma Coptidis), Chinese pulsatilla root (Radix Pulsatillae), etc., in order to enhance its dysentery-relieving effect. 



In addition, the honeysuckle flower can be distilled with water into Jinyinhua Lu (honeysuckle flower distillate), which can clear away summer heat, and therefore it is used for such ailments as excessive thirst due to summer heat, sore throat and infantile herpes simplex, prickly heat, etc. 

8.Psyche:Emotional Healing 

A remedy of choice when clearing past-life issues, this assists shifting into the present from past-life issues holding one back; specific for past-life work, releasing limitations. Often there is soul-scarring from loss, or lack of mastery regarding lessons previously presented 

Floral Remedies are for helping people regain hope and live for the present. Floral remedies help people who tend to live in the past and are obsessive on the missed opportunities in life. Floral remedies are easy to take and are found in health food stores. 

If you are ready to try something different then you may want to try a floral remedy.Honeysuckle has been used for over fifty years to help promote emotional healing. Honeysuckle can help people regain hope and live for the present. The type of Honeysuckle used for floral therapy has slim petals of flowers and are red on the outside and white on the inside but hey turn yellow after they have been pollinated. These types of Honeysuckle are a climbing plant with can grow up to twelve feet high. The berries of the Honeysuckle are toxic and you should keep away from them. 


You can find floral remedies in most health food stores. They are usually bottled as a flower essence and come in different kinds of flower essences. You can make your own remedy with the flower essence or combination of essences by mixing them in spring water and sip the mixture several times a day. 

Honeysuckle has a relaxing, revitalizing effect that is used to help people overcome a negative outlook on life. Honeysuckle flowers can build up concentration and optimism about the present and future. People who are the most likely to benefit from honeysuckle therapy have deep regrets about their past or they may be having a hard time dealing with the loss of a loved one. Honeysuckle can help people confront and move beyond suppressed, painful and past experiences. 

You can make a wildflower mixture to help feel better. You can combine honeysuckle with star of Bethlehem for the relief of grief following the death or tragedy of a loved one. Add three drops of wildflower mixture to a half ounce of water and sip it slowly. If you are feeling like you could use help to get a more positive, mental outlook you may want to try wildflower remedies. 

If you use the flower remedies you may see signs of improvement in yourself such as a positive outlook and you may be more alert. Your mind may open up to more possibilities and you may feel joy. You will feel more optimistic about the future and you may get more initiative and creativity. You will feel more optimistic about the present and the future.Floral remedies may seem strange if you have never heard of them before but once you are used to them they can provide emotional help. 

Honeysuckle flower essence is used to help people regain a good outlook on everyday life. It will instill optimisim regarding the present and future. Usually the one that will benefit most from honeysuckle flower essence is one that is focused on the bad thing that have happened to them in the past. 

Honeysuckle flower essence may also benefit children who have had a traumatic occurance in their life. It can help with homesickness, feelings that they are responsible for their parent's divorce, too much change in a short period of time, and for children who cry quite a bit of the time. In these circumstances, honeysuckle may build a child's confidence and reduce distress. 


Pharmacology:Honeysuckle flower 

Properties: Sweet in flavor, cold in nature, it is related to the lung, stomach and large intestine channels. 

Functions: Clears away heat, removes toxic substances and expels wind and heat pathogens. 

Mechanism: Western applications of Lonicera caprifolium (HONEYSUCKLE) tend to follow the age old usage, that is, the leaves are used as a gargle or mouthwash for sore throats and gum problems, while the flowers are commonly used in treatments for asthma, where they relax the airways. The Chinese usage of Lonicera japonica (JIN YIN HUA) is much more extensive, and research has shown an antibacterial action against both streptococcus and staphylococcus bacteria. In laboratory experiments, some protective effects on the lungs have been demonstrated in cases of tuberculosis. Traditional Chinese applications include cases of abscesses or swellings, especially of the breast, throat, eyes, or internally. Honeysuckle is also used in the early stages of diseases accompanied by fever, sensitivity to wind, sore throat, and headache. Honeysuckle is also used in cases of damp-heat dysenteric disorders, or painful urinary dysfunction. The Chinese properties are sweet and cold. 

Anti-pyretic effect: Injecting Jin Yin Hua solution can lower the temperature in rabbits of endotoxin-induced fever, and this effect can last up to four hours.This herb has remarkable anti-inflammatory and antipyretic effects. The water and alcohol infusions of the honeysuckle flower have an obvious cytotoxic effect on Sarcoma 180 and ascites sarcoma. This herb can reduce cholesterol to a certain extent. 

Lowering the cholesterol level: Administered to mice, Jin Yin Huo can inhibit alloxan-induced increase in blood sugar. Jin Yin Hua can decrease mice's serum cholesterol level, increasing their high-density lipoprotein-cholesterol level, and therefore reducing their risk at atherosclerosis. 

Anti-bacterial function: Jin Yin Hua has a relatively strong inhibitory effect on a number of bacteria, including Staphylococcus aureus, E. coli, Pseudomonus aeruginosa, typhoid bacillus, Candida albicans, pyloric spirillum, and gonococcus.With its broad-spectrum antimicrobial effects, it has stronger inhibitory effects on such pathogenic bacteria as Staphylococcus aureus, Bacillus dysenteriae, etc., and inhibitory effects on a variety of pathogenic micro-organisms such as leptospirae, influenza virus and pathogenic moulds. 

Counteracting activated oxygen: Experiments show that Jin Yin Hua can eliminate H2O2, and the intensity of this effect is proportional to the quantity of the herb applied. 


Magical Detoxifying honeysuckle: 

In Chongning period of Song Dynasty, natural disaster constant year after year, the people had no means of livelihood. The Buddhist monks, in Baiyun Temple on Tianping mountain of Suzhou, begged alms but could get nothing, so they had to live on potherbs. One day, they were very glad to find some beautiful mushrooms in the withered wood mountain stream, climbed up the withered tree and picked them. Got back to the temple, they boiled the mushrooms and tasted very delicious. But when it was midnight the monks unexpectedly felt angina in the belly, mouthfuls of saliva, vomit again and again, dizzy, unable all over, critically ill. They had no way of treating except awaiting doom.Among them, one monk over-40-year-old remembered, at that time of the last year, a young monk caught a heavy poisonous sore on the back and had no medicine to cure. 

Later, a visiting monk saw it and pulled out some mandarin duck grass outside temple, cleaned and pounded to pieces applied at the affected part. Five days later, the monk got better miraculously. Since mandarin duck grass could cure malicious sore, could it detoxify fungus poison? Thinking of this, the monk stood up, doddered out of temple, found some mandarin duck grass among miscellaneous grass. After chewing the grass with root and leaf, he felt better, the pain lightened, vomit reduced too. He returned to the temple in a hurry and asked the other monks to eat. Four monks followed him and survived. The others wouldn't chew the grass for its flavor of medical herbs and all died. From then on, when someone got poisoned by malicious mushroom, the monks would cure them with mandarin duck grass. Li Shizhen, pharmacy expert of Ming Dynasty, adopted the recipe in "Compendium of Materia Medica". 

Mandarin duck grass is the whole grass of honeysuckle belonging to honeysuckle evergreen shrub. Honeysuckle has a fruit and 2 flowers, a yellow one and a white one, looks like gold and silver. They are in pairs, just like mandarin ducks, so it is called "mandarin duck rattan", "mandarin duck grass", "two treasure flowers", "a pair of flowers". Honeysuckle can clear fever, detoxify, detumescence and make eyes brighter, evacuate chill, etc. It can cure hot poisonous swollen disease, ache subcutaneous ulcer, hot warm disease, blood dysentery, haemorrhoids, throat aching etc. can cure fever caused by internal hot or external infection, treat b encephailtis and epidemic encephalitis after boiled. Honeysuckle can assist to treat appendicitis and ligated ulceration. In hot summer, honeysuckle boiled with white chrysanthemum, sugar and water can loose heat, solve hot, sterilize and brighten eyes. For moistening throat, as beverage, it can prevent children measles, sore furuncle, etc. The old often drinking it can prolong life, cure deficiency. In recent years, honeysuckle has been made into series of health care beverage such as honeysuckle tea, silver flower crystal, silver flower dew, silver flower wine that have been launched and well received. 

More Applications and function of Honeysuckle flower.:


1. Affection by exopathogenic wind: heat or epidemic febrile diseases at the early stage, manifested as fever and slight aversion to wind and cold. It is often used with forsythia fruit and peppermint, as in Powder of Lonicera and Forsythia (Yin Qiao San). 

2. Invasion of the qi system by pathogenic heat marked by high fever, dire thirst and full pulse: It is often used with gypsum and anemarrhena rhizome. 

3. Sores, car- buncles, furuncles and swelling: It is a very important herb for external diseases, usually used in combination with dandelion and viola herb, as in Antiphlogistic Decoc- tion of Five Herbs. (Wuwei Xiaodu Yin). 4. Diarrhea and dysentery with puru- lent and bloody stool. It is often used with scutellaria root, coptis root and pulsatilla root, or used alone to prepare a concentrated decoc- tion for frequent drink. 

4. Honeysuckle is edible and medicinal: High in Calcium, Magnesium, and Potassium, the leaves can be parboiled and eaten as a vegetable. The edible buds and flowers, made into a syrup or puddings. 

5. Nutrition: The entire plant has been used as an alternative medicine for thousands of years in Asia. The active constituents include calcium, elaidic-acid, hcn, inositol, linoleic-acid, lonicerin, luteolin, magnesium, myristic-acid, potassium, tannin, and zink. Some of this plant's complex chemistry is discussed in the experimental trials listed below.


6. Upper respiratory tract infections: Honeysuckle is particularly good for upper respiratory tract infections. The stems and flowers are used together in infusion or decoction. 

7. The stems: are used internally in the treatment of acute rheumatoid arthritis, mumps and hepatitis. 

8. Blood Pressure: Honeysuckle is alterative, antibacterial, antiinflammatory, antispasmodic, diuretic, febrifuge, and is also used to reduce blood pressure. 

9. Polyphenolic compounds:  isolated from Lonicera japonica inhibit human platelet activation and provide protection from cellular injury, and thus help maintain human vascular homeostasis. 

10. Experimentally:Blood cholesterol the flower extracts have been shown to lower blood cholesterol levels and are antibacterial, antiviral and tuberculostatic. 

11. Externally:Skin Benefit  the flowers are applied as a medicinal wash to skin inflammations, infectious rashes and sores. 

12. Leaves and flowers: are traditionally used to treat chicken pox. 

13. Medicinal virtues: The leaves are the only parts used and are put into gargarisms for sore throats. Some recoinmenda decoction for a cough and the phthisic and to open obstructions of the liver and spleen. 

Cosmetic Uses of Honeysuckle


Honeysuckle extract is a fragrant plant extract that can be a skin irritant, but may also have anti-irritant properties.Lonicera Caprifolium Flower Extract is a kind of Honeysuckle Extract derived from the flower bud of Lonicera Caprifolium,this kind of Honeysuckle Flower Extract help stimulates the removal of toxins and waste materials to promote vibrant skin, rich in ochnaflavones that provide antiviral actions. 


Lonicera Japonica Flower Extract is a kind of Honeysuckle Extract derived from the flower bud of Lonicera Japonica,this kind of Honeysuckle Flower Extract help stimulates the removal of toxins and waste materials to promote vibrant skin, rich in ochnaflavones that provide antiviral actions, anti-inflammatory and anti-fungal properties. 

Honeysuckle flower:Suggestions and Administration.:


Suggestive Dosage: 

10- 15g, decocted in water for an oral dose. 


Contraindication: For a person with deficient and cold symptoms.Pregnant and nursing women should not use Honeysuckle. 

Precautions:Exercise caution when administering to patients with cold in the stomach and the spleen, and to patients of sores as yin-symptom complexes 

This herb should be avoided by anyone with deficiency of spleen-yang or with skin and external diseases with watery pus due to qi deficiency. 

Honeysuckle flower's leaves and stems contain saponins. Saponins are quite toxic but are poorly absorbed by the human body and so most pass through without harm. They can be found in many common foods such as some beans. Thorough cooking, and perhaps changing the cooking water once, will normally remove most of the saponins. 

Saponins are much more toxic to some creatures, such as fish, and hunting tribes have traditionally put large quantities of them in streams, lakes, etc., in order to stupefy or kill the fish. 

Modern uses: The Honeysuckle is laxative, expectorant, diuretic, diaphoretic and emetic. It contains natural antibiotics and salicylic acid from which aspirin is produced. The leaves are used as an infusion, one part to 100 parts of boiling water, as a laxative. The flowers, used in the same proportions, are taken for coughs, catarrh and asthma, or may be made into a syrup by adding honey until the mixture thickens. The dose is one teaspoonful.Taken in large doses, the plant is emetic and toxic. 


Honeysuckle flower:Applications 


Infusion - Combine with other expectorant herbs, such as cowslip, elecampane, or mulberry, for coughs and mild asthma. 

Syrup - Take a syrup made with the infusion for coughs. Can be combined with other expectorant flowers, such as mullein or marshmallow. 

Flower Buds: 

Decoction:Take in the early stages of a feverish cold characterized by a headache, thirst, and sore throat. Use 10 - 15 g herb to 600 ml water. Add huang lian and huang qin for high fevers. 

Tincture:Use for diarrhea or gastroenteritis related to food poisoning. 


Decoction- Make with 15 - 30 g herb to 600 ml water and use as the flower bud decoction, especially if there are painful joints, as in influenza. Combine with other cooling herbs, such as luo shi teng or shi hu, for inflammatory diseases, for example, rheumatoid arthritis. 

Honeysuckle Tea: 

Gather two cups of leaves and flowers from wild Honeysuckle vines(make sure they haven't been sprayed). If you can't get the flowers, leave them out of the recipe. Bring 1 quart of water to a boil and add the two cups of honeysuckle leaves. Gently simmer for 10 minutes and strain. 

Add the "tea" back to the pot and add 1 cup of honey, bring to a boil and boil for one minute and remove from heat. Add any flavorings at this time to the syrup. Deborah says her children love it when she adds one packet of lime Kool-aide. Store in fridge up to a month or freeze in small batches and take out what you need at one time. This cured a strep throat in Deborah's daughter during a severe mono infection when no antibiotics would work. Now it has been a standby in her home for over 10 years. 

Dosage: 1 oz every two hours for 5 yr. olds and up to adult. 


Honeysuckle flower:Toxicity Study 

Toxicity of Honeysuckle flower extract: LD50 (mice/hypodermic injection/herb extract): 53g/kg. 

Identification of Chlorogenic acid: 

Chemical Name:Cyclohexanecarboxylic acid,3-((3-(3,4-dihydroxyphenol)1-oxo-2-propenyl)oxy)-1,4,5-trihydroxy-,(1S-(1-alpha,3-beta,4-alpha,5-alpha))- 

CAS RN.:327-97-9. M.F.Molecular Formula.C16-H18-O9. Molecular Weight.M.W.354.34 RTECS:GU8480000 EINECS:206-325-6. 

Synonyms:3-Caffeoylquinic acid;3-O-Caffeoylquinic acid;Chlorogenic acid;(1S,3R,4R,5R)-3-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid; 3-O-Caffeoylquinic acid; 5-O-(3,4-Dihydroxycinnamoyl)-L-quinic acid 

Note:Mutagen,Reproductive Effector,Natural Product. 

Melting point:205-209 deg C. alpha:-36 (c=1, H2O) Water solubility:soluble in hot water. 


Acute Toxicity of Chlorogenic acid 

LDLo-Lowest published lethal dose.Intraperitoneal.Rodent-rat.4 gm(4000mgs)/kg. 

Details of toxic effects not reported other than lethal dose value. 

Reference:TXAPA9 Toxicology and Applied Pharmacology.(Academic Press,Inc.,1E.First St.,Duluth,MN 55802)V.1-1959-Volume(issue)/page/year:36,227,1976. 

Reproductive Date:Chlorogenic acid 

TDLo-Lowest published toxic dose.Intraperitoneal.Rodent-rat.40 mg/kg.Sex/Duration:female 5~12 day(s) after conception. 

Reproductive-Specific Developmental Abnormalities-musculoskeletal system. 

Reference:TXAPA9 Toxicology and Applied Pharmacology.(Academic Press,Inc.,1E.First St.,Duluth,MN 55802)V.1-1959-Volume(issue)/page/year:36,227,1976. 

Mutagenic Date:Chlorogenic acid 

Gene conversion and mitotic recombination.Yeast-Saccharomyces cerevisiae.1 gm/L.Reference:MUREAV Mutation Research.(Elsevier Science Pub.B.V.,POB 211,1000 AE Amsterdam,Netherlands)V.1-1964-Volume(issue)/page/year:135,109,1984. 

Mutation in microorganisms.Rodent-mouse Lymphocyte.6545 mg/L.Reference:MUREAV Mutation Research.(Elsevier Science Pub.B.V.,POB 211,1000 AE Amsterdam,Netherlands)V.1-1964-Volume(issue)/page/year:204,219,1988. 

Cytogenetic analysis.Rodent-hamster Ovary.250 mg/L.Reference:MUREAV Mutation Research.(Elsevier Science Pub.B.V.,POB 211,1000 AE Amsterdam,Netherlands)V.1-1964-Volume(issue)/page/year:111,209,1983. 

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